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Brain Signal Variability

Blood oxygen-level dependent (BOLD) signal variability is believed to reflect the brain’s dynamic ability to undergo fast moment-to-moment switching through network reconfigurations. One of the projects involving BOLD signal variability aims to examine its relationship to neuroanatomical metrics such as cortical thickness, grey matter volume and cortical area. Another branch of the project concerns examining BOLD signal variability changes across aging in the context of resting-state networks.

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Default Mode Network and Dorsal Attention Network anti-correlation predicts BOLD signal variability in left intraparietal sulcus and left middle frontal gyrus in older adults

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